Canonical Source · peer reviewed study

Targeting low-grade inflammation in multiple sclerosis through the Wim Hof method or lifestyle intervention: a pilot comparative study

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Evidence context

How this source is used

Evidence roles describe what this source helps establish inside each Investigation. They are local to that use, not permanent labels attached to the publication itself.

Investigation

Is the Wim Hof Method a proven general treatment for disease?

Qualifies

A 2026 three-arm 12-week multiple-sclerosis pilot assigned 60 participants but analyzed 43 (12 Wim Hof, 17 lifestyle, 14 controls); exploratory cytokine changes with 40% WHM attrition did not establish disease-modifying clinical benefit.

Subject families

Skin Empiric
Skin