Quantification of objective concentrations of DNA impurities in mRNA vaccines
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Original vaccine-vial analyses used different materials and preparations: Kaiser (6 vials) tested RNA/lipid interference and validated with LC-MS, Speicher (32 vials across 16 lots) reported contested high estimates, and Achs (15 batches, 11 expired) applied qPCR, fluorometry, capillary electrophoresis and sequencing. These measure manufacturing residual DNA, not stable insertion into vaccinated human chromosomes.