Canonical Source · peer reviewed study

Association of alkalization therapy with long-term survival in stage IV or recurrent colorectal cancer: interaction with RAS mutation status

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Publisher: Frontiers in Oncology
Year: 2026
DOI: 10.3389/fonc.2026.1867616
Source type: peer reviewed study
Source level: Primary source
Knowledge backlinks: 1

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Evidence context

How this source is used

Evidence roles describe what this source helps establish inside each Investigation. They are local to that use, not permanent labels attached to the publication itself.

Investigation

Can an alkaline diet prevent disease by stopping the body from becoming acidic?

Qualifies

Three 2025–2026 same-clinic retrospective observational publications report survival correlations with urinary pH in selected cancer cohorts, including 203 NSCLC and 129 colorectal patients. Likely overlapping clinic/date cohorts, other anticancer care, nonrandom selection and no blood or tumor-pH demonstration prevent an inference that diet alkalizes blood or treats cancer.

Subject families

Food & chemistry Health & medicine