Canonical Source · peer reviewed study

A Randomised Cross-Over Pharmacokinetic Bioavailability Study of Synthetic versus Kiwifruit-Derived Vitamin C

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Publisher: Nutrients
Year: 2013
DOI: 10.3390/nu5114451
Source type: peer reviewed study
Source level: Primary source
Knowledge backlinks: 1

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Evidence context

How this source is used

Evidence roles describe what this source helps establish inside each Investigation. They are local to that use, not permanent labels attached to the publication itself.

Investigation

Is 'left-handed' natural vitamin C different from 'right-handed' synthetic vitamin C?

Qualifies

In a nine-participant randomized crossover comparison of 200 mg synthetic vitamin C versus an equivalent amount from kiwifruit, plasma exposure did not significantly differ (plasma AUC p=0.483), but urinary vitamin C excretion was higher following the fruit (urinary AUC p=0.004). This short-term matrix-related finding does not establish different vitamin C stereoisomers or clinical outcomes.

Subject families

Food & chemistry Health & medicine