Investigation
Does fasting provide metabolic benefits independent of calorie restriction and weight loss?
A 12-week isocaloric controlled-feeding RCT randomized 41 adults with obesity and prediabetes or diet-controlled diabetes; restricted 10-hour versus usual eating windows showed similar weight changes (−2.3 vs −2.6 kg; difference 0.3 kg, 95% CI −1.2 to 1.9) and no significant glycemic advantage.