Investigation
Are natural ingredients generally safer than synthetic ones simply because they are natural?
Contextualizes
Manufacturing, extraction, concentration and contamination can matter for a specific product, but those measurable properties are different from a blanket natural-versus-synthetic safety rule.
Challenges
NCCIH and FDA guidance explicitly warn that natural origin does not establish safety; natural products can be toxic, allergenic or interact with medicines.
Qualifies
Public-health guidance warns that a natural ingredient may interact with medicines or carry toxic dose/contaminant issues; product and measured exposure are the proper unit of safety assessment.